Jagged-1 protein active peptide fragment

$ 95.00

Select Size:

  • JAG-1-pep, 100 µg95.00
Add to Cart
Source M.W. CAS No.
Structural Info
FormulationLyophilized in a solution of acetonitrile and TFA.
ReconstitutionBefore reconstitution, we recommend a brief spin to drive down any material dislodged from the bottom of the tube.  The lyophilized peptide should be reconstituted in 10mM HCl or acetic acid.
StabilityThe lyophilized protein is stable for at least 1 year if stored at -80 °C. Reconstituted protein is stable for at least 1 month at 4 °C, but should be stored in aliquots at -80 °C for longer term. Avoid repeated freeze and thaw.
PurityGreater than 95% as determined by RP-HPLC analysis
Biological ActivityNot determined.
Country of OriginUSA

The Notch pathway is an important pathway in stem cell functions. Jagged-1 is a ligand for Notch receptors. This peptide with a sequence of CDDYYYGFGCNKFCRPR has been shown to mimic the function of full-length Jagged-1, and therefore, can be used as an agonist to activate the Notch pathway. 
Ref: Nickoloff et al, Cell Death Different, 2002;  Sato T et al, Nature, 2009

Nickoloff et al, Cell Death Different, 2002; Sato T et al, Nature, 2009