|Formulation||Lyophilized in a solution of acetonitrile and TFA.|
|Reconstitution||Before reconstitution, we recommend a brief spin to drive down any material dislodged from the bottom of the tube. The lyophilized peptide should be reconstituted in 10mM HCl or acetic acid.
|Stability||The lyophilized protein is stable for at least 1 year if stored at -80 °C. Reconstituted protein is stable for at least 1 month at 4 °C, but should be stored in aliquots at -80 °C for longer term. Avoid repeated freeze and thaw.
|Purity||Greater than 95% as determined by RP-HPLC analysis|
|Biological Activity||Not determined.|
|Country of Origin||USA|
The Notch pathway is an important pathway in stem cell functions. Jagged-1 is a ligand for Notch receptors. This peptide with a sequence of CDDYYYGFGCNKFCRPR has been shown to mimic the function of full-length Jagged-1, and therefore, can be used as an agonist to activate the Notch pathway.
Ref: Nickoloff et al, Cell Death Different, 2002; Sato T et al, Nature, 2009